What do you mean? Global prefs are already common. Are you imagining the ability to logically separate user prefs into two classes - game play style and game play events - and have something that changes all of the play style prefs in user file B so that they are the same as the play style prefs in user file A?
If that is the case I'm not aware of anything that does that other than deleting the files and letting mafia recreate them with the same defaults. This, of course, has the side effect of losing or resetting all of the game play events which is usually not what is wanted.
I suspect it would not be too difficult to write something that read a file with preference name, value pairs and then set the preference to that value for the logged in account. That effectively makes certain user preferences global.
Given that this is just a straight text substitution, it might make more sense to do it outside of mafia.
If the preference files allow for multiple instances of a preference then you could do this on a one time basis by appending the desired preferences to the end of the user preferences and running mafia once. It would presumably read the file, update the preferences with the "last" value from the file and then write it out.
This suggests to me that you might want to focus the question by generating a list of the preferences to be synchronized.